Endocrine Abstracts

Topiramate is an antiepileptic drug, with anoressant effect, known to positively modulate GABA receptors. There are some published data concerning the use of topiramate in mood disorders (expecially BED), while there are not know data on its use in obese patients without BED. This is a preliminary study to explane the effectiveness and tolerability of topiramate in non-Binge Eating Disorder (BED) obese patients with metabolic syndrome. We described the effects of topiramate, w...

Metabolic Syndrome (MetS) is characterized by the association of insulin resistance, hypertension, dyslipidemia, non-alcoholic fatty liver disease, and is strictly related to increased cardiovascular risk. Recent scientific evidence confirms that very low calorie ketogenic diet (VLCKD) is a valuable treatment for patients with insulin resistance and visceral obesity. After the VLCKD phase it is essential to gradually reintroduce carbohydrates and increase calories in order to ...

Adrenal masses are among the most prevalent human tumors and are frequently detected unexpectedly by imaging studies performed for reasons unrelated to suspect of adrenal diseases.Subclinical hypercortisolism (SH) is the most frequent endocrine dysfunction detected in patients with adrenal incidentalomas (AI), accounting from five to 20% of all cases depending on inclusion criteria. one mg overnight dexamethasone suppression test (one mg DST) should be t...

Primary amenorrhea is a rare disease that affects <1% of adolescent girls. The most common causes of primary amenorrhea include chromosomal abnormalities, hypothalamic and pituitary disorders, lack or structural abnormality of reproductive organs.18 years old woman was referred to us by her pediatric physician for evaluation of primary amenorrhea and hirsutism. She had low birth weight, 1.9 kg, and hypostaturism. At the age of 6 years underwent to cl...

Background: Riedel’s thyroiditis (RT) is a rare thyroid disease. Clinical and citological differential diagnosis with thyroid malignancy is difficult pre-operatively and often only pathological report may confirm the diagnosis.Methods: We report a case of a 72-year-old Italian woman with a known history of goiter, which showed a rapid increase in size at ultrasound check, suggesting malignancy. Based on non-diagnostic cytology (Thy 1), a total thyro...